FAM46C inhibits lipopolysaccharides-induced myocardial dysfunction via downregulating cellular adhesion molecules and inhibiting apoptosis.

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第一作者： Jiaying,Tan

第一单位： Department of Critical Care Medicine, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, PR China.

作者： Jiaying,Tan ^[1] ; Tao,Sun ^[2] ; Jun,Shen ^[1] ; Huigeng,Zhu ^[1] ; Ye,Gong ^[1] ; Hechen,Zhu ^[1] ; Gang,Wu ^[3]

作者单位： Department of Critical Care Medicine, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, PR China. ^[1] Department of Cardiology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, PR China. ^[2] Department of Critical Care Medicine, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, PR China. Electronic address: wugang@fudan.edu.cn. ^[3]

关键词 FAM46C SIMD Sepsis TLR4

主题词动物(Animals);细胞凋亡(Apoptosis);心肌疾病(Cardiomyopathies);病例对照研究(Case-Control Studies);细胞黏附分子(Cell Adhesion Molecules);细胞增殖(Cell Proliferation);人类(Humans);脂多糖类(Lipopolysaccharides);MAP激酶信号系统(MAP Kinase Signaling System);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肌细胞, 心脏(Myocytes, Cardiac);核苷酸基转移酶类(Nucleotidyltransferases);聚核苷酸腺嘌呤转移酶(Polynucleotide Adenylyltransferase);蛋白质类(Proteins);脓毒症(Sepsis);信号传导(Signal Transduction);Toll样受体4(Toll-Like Receptor 4)

DOI 10.1016/j.lfs.2019.03.048

PMID 30910647

发布时间 2019-12-10

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Life sciences

2019年229卷

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FAM46C inhibits lipopolysaccharides-induced myocardial dysfunction via downregulating cellular adhesion molecules and inhibiting apoptosis.

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FAM46C inhibits lipopolysaccharides-induced myocardial dysfunction via downregulating cellular adhesion molecules and inhibiting apoptosis.

Life sciences

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Life sciences

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