Anxiolytic-like effect of chalcone N-{(4'-[(E)-3-(4-fluorophenyl)-1-(phenyl) prop-2-en-1-one]} acetamide on adult zebrafish (Danio rerio): Involvement of the GABAergic system.

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第一作者： Maria Kueirislene A,Ferreira

第一单位： State University of Ceará, Science and Technology Center (CCT), Itaperi Campus, Laboratory of Natural Products Chemistry - LQPN-S, CEP 60741-000, Fortaleza, Ceará, Brazil. Electronic address: kueirislene.ferreira@aluno.uece.br.

作者： Maria Kueirislene A,Ferreira ^[1] ; Antonio Wlisses,da Silva ^[2] ; Francisca Crislândia O,Silva ^[2] ; Carlos Leone A,Holanda ^[2] ; Sheila M,Barroso ^[2] ; Joyce Dos Reis,Lima ^[2] ; Antônio Eufrásio,Vieira Neto ^[3] ; Adriana R,Campos ^[3] ; Paulo N,Bandeira ^[4] ; Hélcio S,Dos Santos ^[4] ; Telma Leda G,de Lemos ^[5] ; Sônia Maria C,Siqueira ^[2] ; Francisco Ernani A,Magalhães ^[6] ; Jane Eire S A,de Menezes ^[7]

作者单位： State University of Ceará, Science and Technology Center (CCT), Itaperi Campus, Laboratory of Natural Products Chemistry - LQPN-S, CEP 60741-000, Fortaleza, Ceará, Brazil. Electronic address: kueirislene.ferreira@aluno.uece.br. ^[1] State University of Ceará, Science and Technology Center (CCT), Itaperi Campus, Laboratory of Natural Products Chemistry - LQPN-S, CEP 60741-000, Fortaleza, Ceará, Brazil. ^[2] University of Fortaleza, Experimental Biology Nucleus (NUBEX), CEP 60811650, Fortaleza, Ceará, Brazil. ^[3] State University of Vale do Acaraú, Chemistry Course, Laboratory of Natural Products Chemistry, Synthesis and Biocatalysis of Organic Compounds - LBPNSB, Betânia Campus, CEP 62040370, Sobral, Ceará, Brazil. ^[4] Department of Organic and Inorganic Chemistry, Federal University of Ceará, CEP 60451-970, Fortaleza, Ceará, Brazil. ^[5] State University of Ceará, Science and Technology Center (CCT), Itaperi Campus, Laboratory of Natural Products Chemistry - LQPN-S, CEP 60741-000, Fortaleza, Ceará, Brazil; University of Fortaleza, Experimental Biology Nucleus (NUBEX), CEP 60811650, Fortaleza, Ceará, Brazil; State University of Ceará, Department of Chemistry, Laboratory of Natural Products Bioprospecting and Biotechnology, CECITEC Campus, CEP 60660-000, Tauá, Ceará, Brazil. Electronic address: ernani.magalhaes@uece.br. ^[6] State University of Ceará, Science and Technology Center (CCT), Itaperi Campus, Laboratory of Natural Products Chemistry - LQPN-S, CEP 60741-000, Fortaleza, Ceará, Brazil. Electronic address: jane.menezes@uece.br. ^[7]

关键词 Adult zebrafish Anxiolytic-like effect GABA(A)Synthetic chalcone