Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail-mediated epithelial-mesenchymal transition.

导出 OA

翻译打印收藏纠错

作者： Sun-Mi,Park ^[1] ; Seung-Ho,Park ^[2] ; Ki-Jun,Ryu ^[1] ; In-Kyu,Kim ^[1] ; Hyeontak,Han ^[1] ; Hyo-Jin,Kim ^[1] ; Seon-Hee,Kim ^[1] ; Keun-Seok,Hong ^[1] ; Hyemin,Kim ^[1] ; Minju,Kim ^[1] ; Bok Im,Cho ^[3] ; Jeong Doo,Heo ^[3] ; Na Hyun,Kim ^[3] ; Eun Mi,Hwang ^[4] ; Jae-Yong,Park ^[5] ; Jong In,Yook ^[6] ; Hee Jun,Cho ^[7] ; Cheol,Hwangbo ^[1] ; Kwang Dong,Kim ^[8] ; Hoseok,Song ^[1] ; Jiyun,Yoo ^[8]

作者单位： Division of Applied Life Science (BK21 Plus), Research Institute of Life Sciences, Gyeongsang National University, Jinju, Korea. ^[1] Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea. ^[2] Gyeongnam Department of Environmental Toxicology and Chemistry, Toxicology Screening Center, Korea Institute of Toxicology, Jinju, Korea. ^[3] Center for Functional Connectomics, Korea Institute of Science and Technology, Seoul, Korea. ^[4] School of Biosystem and Biomedical Science, College of Health Science, Korea University, Seoul, Korea. ^[5] Department of Oral Pathology, Oral Cancer Research Institute, College of Dentistry, Yonsei University, Seoul, Korea. ^[6] Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea. ^[7] Division of Life Science, Gyeongsang National University, Jinju, Korea. ^[8] Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, Korea. ^[9]

关键词 CHIP E3 ubiquitin ligase EMT cancer metastasis ovarian cancer snail