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Genomic profiling in pancreatic ductal adenocarcinoma and a pathway towards therapy individualization: A scoping review.

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第一作者： Ritu R,Singh

第一单位： Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai St. Luke's and Mount Sinai West, New York, NY 10019, USA. Electronic address: ritu.singh@mountsinai.org.

作者： Ritu R,Singh ^[1] ; Johanna,Goldberg ^[2] ; Anna M,Varghese ^[3] ; Kenneth H,Yu ^[3] ; Wungki,Park ^[3] ; Eileen M,O'Reilly ^[4]

作者单位： Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai St. Luke's and Mount Sinai West, New York, NY 10019, USA. Electronic address: ritu.singh@mountsinai.org. ^[1] MSK Library, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: goldbejb@mskcc.org. ^[2] Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA; David M. Rubenstein Center for Pancreatic Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[3] Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA; David M. Rubenstein Center for Pancreatic Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: oreillye@mskcc.org. ^[4]

关键词 DNA damage repair Genomic alteration (GA)Germline mutation Microsatellite instability Mismatch repair (MMR)Pancreatic ductal adenocarcinoma (PDAC)Somatic mutation

医学主题词动物(Animals);癌, 胰腺管(Carcinoma, Pancreatic Ductal);DNA修复(DNA Repair);基因组学(Genomics);人类(Humans);胰腺肿瘤(Pancreatic Neoplasms)

DOI 10.1016/j.ctrv.2019.03.003

PMID 30927677

发布时间 2025-01-30

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