Phase separation of RNA-binding proteins in physiology and disease: An introduction to the JBC Reviews thematic series.

导出 OA

翻译打印收藏纠错

第一作者： James,Shorter

第一单位： From the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 jshorter@pennmedicine.upenn.edu.

作者： James,Shorter ^[1]

作者单位： From the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 jshorter@pennmedicine.upenn.edu. ^[1]

关键词 Liquid–liquid phase separation RNA-binding protein TAR DNA-binding protein 43 (TDP-43) (TARDBP)amyotrophic lateral sclerosis (ALS) (Lou Gehrig disease)biomolecular condensates frontotemporal dementia fused in sarcoma (FUS)heterogeneous nuclear ribonucleoprotein (hnRNP)membraneless organelles

主题词肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);色谱法, 液相(Chromatography, Liquid);额颞叶痴呆(Frontotemporal Dementia);人类(Humans);神经变性疾病(Neurodegenerative Diseases);RNA结合蛋白质类(RNA-Binding Proteins)

DOI 10.1074/jbc.REV119.007944

PMID 30948513

发布时间 2021-02-05

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交