Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study.

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第一作者： Andrea L,Jorgensen

第一单位： Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, member of Liverpool Health Partners, Liverpool, UK. a.l.jorgensen@liverpool.ac.uk.

作者： Andrea L,Jorgensen ^[1] ; Clare,Prince ^[2] ; Gail,Fitzgerald ^[2] ; Anita,Hanson ^[2] ; Jennifer,Downing ^[3] ; Julia,Reynolds ^[4] ; J Eunice,Zhang ^[5] ; Ana,Alfirevic ^[3] ; Munir,Pirmohamed ^[3]

作者单位： Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, member of Liverpool Health Partners, Liverpool, UK. a.l.jorgensen@liverpool.ac.uk. ^[1] The Royal Liverpool and Broadgreen University Hospitals NHS Trust and Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. ^[2] Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, member of Liverpool Health Partners, Liverpool, UK. ^[3] NIHR Collaboration for Leadership in Applied Health Research and Care, North West Coast, UK. ^[4] Innovation Agency, Academic Health Science Network for the North West Coast, Daresbury, Warrington, UK. ^[5] MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool and The Royal Liverpool and Broadgreen University Hospitals NHS Trust, members of Liverpool Health Partners, Liverpool, UK. ^[6]

关键词 Anticoagulation Genotype-guided dosing Implementation study Pharmacogenetics Point-of-care Warfarin