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D<sub>2</sub> Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine.

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第一作者： Yudao,Shen

第一单位： Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States.

作者： Yudao,Shen ^[1] ; John D,McCorvy ^[2] ; Michael L,Martini ^[1] ; Ramona M,Rodriguiz ^[3] ; Vladimir M,Pogorelov ^[3] ; Karen M,Ward ^[4] ; William C,Wetsel ^[3] ; Jing,Liu ^[1] ; Bryan L,Roth ^[5] ; Jian,Jin ^[1]

作者单位： Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States. ^[1] Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program, School of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.;Department of Cell Biology, Neurobiology and Anatomy , Medical College of Wisconsin , Milwaukee , Wisconsin 53226 , United States. ^[2] Departments of Psychiatry and Behavioral Sciences, Cell Biology, and Neurobiology , Duke University Medical Center , Durham , North Carolina 27710 , United States. ^[3] Worldwide Research and Development , Internal Medicine Research Unit, Pfizer , Cambridge , Massachusetts 02139 , United States. ^[4] Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program, School of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States. ^[5]