TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach.

导出 OA

翻译打印收藏纠错

作者： Jana,Zecha ^[1] ; Shankha,Satpathy ^[2] ; Tamara,Kanashova ^[3] ; Shayan C,Avanessian ^[2] ; M Harry,Kane ^[2] ; Karl R,Clauser ^[2] ; Philipp,Mertins ^[4] ; Steven A,Carr ^[5] ; Bernhard,Kuster ^[6]

作者单位： From the ‡Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany. ^[1] §Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA. ^[2] ¶Max Delbrück Center for Molecular Medicine in the Helmholtz Society, Berlin, Germany. ^[3] §Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA;; ¶Max Delbrück Center for Molecular Medicine in the Helmholtz Society, Berlin, Germany;; ‖Berlin Institute of Health, Berlin, Germany. ^[4] §Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA;. Electronic address: scarr@broad.mit.edu. ^[5] From the ‡Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany;; **Bavarian Biomolecular Mass Spectrometry Center (BayBioMS), TUM, Freising, Germany. Electronic address: kuster@tum.de. ^[6]

关键词 Labeling Efficiency NHS Ester Chemistry Peptides*Phosphoproteome Post-Translational Modifications*Quantification Stable Isotope Labeling Tandem Mass Spectrometry Tandem Mass Tags