Interleukin-21 enhances Toll-like receptor 2/4-mediated cytokine production via phosphorylation in the STAT3, Akt and p38 MAPK signalling pathways in human monocytic THP-1 cells.
第一作者:
Leilei,Jian
第一单位:
Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing, China.
作者:
医学主题词
细胞系, 肿瘤(Cell Line, Tumor);细胞因子类(Cytokines);人类(Humans);白细胞介素类(Interleukins);单核细胞(Monocytes);磷酰化(Phosphorylation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 白细胞介素21(Receptors, Interleukin-21);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);Toll样受体2(Toll-Like Receptor 2);Toll样受体4(Toll-Like Receptor 4);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1111/sji.12761
PMID
30977163
发布时间
2025-01-03
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