Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice.

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作者： Luke,Harrison ^[1] ; Katrin,Pfuhlmann ^[1] ; Sonja C,Schriever ^[2] ; Paul T,Pfluger ^[3]

作者单位： Research Unit Neurobiology of Diabetes, Helmholtz Zentrum München, 85764, Neuherberg, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, 85764, Neuherberg, Germany; German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany; Division of Metabolic Diseases, Technische Universität München, 80333, Munich, Germany. ^[1] Research Unit Neurobiology of Diabetes, Helmholtz Zentrum München, 85764, Neuherberg, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, 85764, Neuherberg, Germany; German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany. ^[2] Research Unit Neurobiology of Diabetes, Helmholtz Zentrum München, 85764, Neuherberg, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, 85764, Neuherberg, Germany; German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany. Electronic address: paul.pfluger@helmholtz-muenchen.de. ^[3]

关键词 Astrocyte Hypothalamus Inflammation Obesity Reactive gliosis Weight loss

主题词动物(Animals);减肥药(Anti-Obesity Agents);星形细胞(Astrocytes);钙结合蛋白质类(Calcium-Binding Proteins);热量限制(Caloric Restriction);神经胶质原纤维酸性蛋白质(Glial Fibrillary Acidic Protein);神经胶质增生(Gliosis);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);微丝蛋白质类(Microfilament Proteins);肥胖症(Obesity);体重减轻(Weight Loss)

DOI 10.1016/j.molmet.2019.03.009

PMID 30979678

发布时间 2020-04-15

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Molecular metabolism

2019年24卷

149-155页

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Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice.

Molecular metabolism

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Molecular metabolism

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Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice.

Molecular metabolism

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Molecular metabolism

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