Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer.

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作者： Natalia,Guillén Díaz-Maroto ^[1] ; Rebeca,Sanz-Pamplona ^[2] ; Mireia,Berdiel-Acer ^[3] ; Francisco J,Cimas ^[1] ; Elena,García ^[1] ; Samuel,Gonçalves-Ribeiro ^[1] ; Nerea,Albert ^[1] ; Gemma,Garcia-Vicién ^[1] ; Gabriel,Capella ^[4] ; Victor,Moreno ^[2] ; Ramon,Salazar ^[5] ; Alberto,Villanueva ^[1] ; David G,Molleví ^[5]

作者单位： ProCURE, Program Against Cancer Therapeutic Resistance, Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain. ^[1] Biomarker and Susceptibility Unit, Program for Cancer Control and Prevention, Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain. ^[2] German Cancer Research Center, Division of Molecular Genome Analysis, Heidelberg, Germany. ^[3] Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain. ^[4] ONCOBELL Program, IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain. ^[5] ProCURE, Program Against Cancer Therapeutic Resistance, Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain. dgmollevi@iconcologia.net. ^[6]