N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.

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作者： Ankit,Sinha ^[1] ; Ali,Hussain ^[1] ; Vladimir,Ignatchenko ^[2] ; Alexandr,Ignatchenko ^[2] ; Kwan Ho,Tang ^[3] ; Victor W H,Ho ^[2] ; Benjamin G,Neel ^[4] ; Blaise,Clarke ^[5] ; Marcus Q,Bernardini ^[6] ; Laurie,Ailles ^[7] ; Thomas,Kislinger ^[8]

作者单位： University of Toronto, Department of Medical Biophysics, Toronto, ON M5G 1L7, Canada. ^[1] Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. ^[2] Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA. ^[3] Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA. ^[4] Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada; University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON M5S 1A8, Canada. ^[5] Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada; University of Toronto, Department of Obstetrics and Gynaecology, Toronto, ON M5G 1E2, Canada. ^[6] University of Toronto, Department of Medical Biophysics, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. ^[7] University of Toronto, Department of Medical Biophysics, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address: thomas.kislinger@utoronto.ca. ^[8]

关键词 N-glycosylation biomarker ovarian cancer patient-derived xenograft serum proteomics targeted proteomics

主题词动物(Animals);癌(Carcinoma);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);糖组学(Glycomics);糖蛋白类(Glycoproteins);人类(Humans);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);卵巢肿瘤(Ovarian Neoplasms);蛋白质组学(Proteomics)

DOI 10.1016/j.cels.2019.03.011

PMID 30981729

发布时间 2020-07-03

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Cell systems

2019年8卷4期

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N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.

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N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.

Cell systems

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