In Vivo Phenotyping of Familial Parkinson's Disease with Human Induced Pluripotent Stem Cells: A Proof-of-Concept Study.

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第一作者： Ourania,Zygogianni

第一单位： Laboratory of Cellular and Molecular Neurobiology - Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521, Athens, Greece.;Faculty of Nursing, University of Athens, 11527, Athens, Greece.

作者： Ourania,Zygogianni ^[1] ; Nasia,Antoniou ^[2] ; Maria,Kalomoiri ^[2] ; Georgia,Kouroupi ^[2] ; Era,Taoufik ^[3] ; Rebecca,Matsas ^[4]

作者单位： Laboratory of Cellular and Molecular Neurobiology - Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521, Athens, Greece.;Faculty of Nursing, University of Athens, 11527, Athens, Greece. ^[1] Laboratory of Cellular and Molecular Neurobiology - Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521, Athens, Greece. ^[2] Laboratory of Cellular and Molecular Neurobiology - Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521, Athens, Greece. etaoufik@pasteur.gr. ^[3] Laboratory of Cellular and Molecular Neurobiology - Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521, Athens, Greece. rmatsa@pasteur.gr. ^[4]

关键词 6-OHDA striatal lesions Alpha-synuclein Cell transplantation Dopaminergic neurons In vitro disease modeling Motor behavior