Clinical and Biological Significance of <i>ESR1</i> Gene Alteration and Estrogen Receptors Isoforms Expression in Breast Cancer Patients.

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第一作者： Anna,Nagel

第一单位： Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. anna.nagel@biotech.ug.edu.pl.

作者： Anna,Nagel ^[1] ; Jolanta,Szade ^[2] ; Mariola,Iliszko ^[3] ; Julia,Elzanowska ^[4] ; Marzena,Welnicka-Jaskiewicz ^[5] ; Jaroslaw,Skokowski ^[6] ; Grzegorz,Stasilojc ^[7] ; Jacek,Bigda ^[8] ; Rafal,Sadej ^[9] ; Anna,Zaczek ^[10] ; Aleksandra,Markiewicz ^[11]

作者单位： Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. anna.nagel@biotech.ug.edu.pl. ^[1] Department of Pathology, Medical University of Gdansk, 80-210 Gdansk, Poland. jszade@gumed.edu.pl. ^[2] Department of Biology and Genetics, Medical University of Gdansk, 80-211 Gdansk, Poland. milisz@gumed.edu.pl. ^[3] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. julia.elzanowska@gmail.com. ^[4] Department of Surgical Oncology, Medical University of Gdansk, 80-211 Gdansk, Poland. mwelj@gumed.edu.pl. ^[5] Department of Oncology and Radiotherapy, Medical University of Gdansk, 80-210 Gdansk, Poland. jskokowski@gumed.edu.pl.;Department of Medical Laboratory Diagnostics -Biobank, Medical University of Gdansk, Gdansk, 80-210 Gdansk, Poland. jskokowski@gumed.edu.pl.;Biobanking and Biomolecular Resources Research Infrastructure (BBMRI.PL), 80-210 Gdansk, Poland. jskokowski@gumed.edu.pl. ^[6] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. gstasilojc@gumed.edu.pl. ^[7] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. jjbigd@gumed.edu.pl. ^[8] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. rsadej@gumed.edu.pl. ^[9] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. azaczek@gumed.edu.pl. ^[10] Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, 80-211 Gdansk, Poland. aleksandra.markiewicz@biotech.ug.edu.pl. ^[11]

关键词 ERα36, ERα66, gene amplification breast cancer estrogen receptor prognostic factor