Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

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第一作者： Carmen,Festa

第一单位： Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, Naples 80131, Italy.

作者： Carmen,Festa ^[1] ; Claudia,Finamore ^[1] ; Silvia,Marchianò ^[2] ; Francesco Saverio,Di Leva ^[1] ; Adriana,Carino ^[2] ; Maria Chiara,Monti ^[3] ; Federica,Del Gaudio ^[3] ; Sara,Ceccacci ^[3] ; Vittorio,Limongelli ^[1] ; Angela,Zampella ^[4] ; Stefano,Fiorucci ^[1] ; Simona,De Marino ^[2]

作者单位： Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, Naples 80131, Italy. ^[1] Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Perugia 06132, Italy. ^[2] Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno 84084, Italy. ^[3] Faculty of Biomedical Sciences, Institute of Computational Science - Center for Computational Medicine in Cardiology, Università della Svizzera italiana (USI), Via G. Buffi 13, Lugano CH-6900, Switzerland. ^[4]

DOI 10.1021/acsmedchemlett.8b00534

PMID 30996787

发布时间 2020-09-28

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ACS medicinal chemistry letters

2019年10卷4期

504-510页

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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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