Motor cortex metabolite alterations in amyotrophic lateral sclerosis assessed in vivo using edited and non-edited magnetic resonance spectroscopy.

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第一作者： A,Weerasekera

第一单位： Biomedical MRI Unit/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.

作者： A,Weerasekera ^[1] ; R,Peeters ^[2] ; D,Sima ^[3] ; T,Dresselaers ^[2] ; S,Sunaert ^[2] ; J,De Vocht ^[4] ; K,Claeys ^[4] ; S,Van Huffel ^[5] ; P,Van Damme ^[6] ; U,Himmelreich ^[7]

作者单位： Biomedical MRI Unit/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium. ^[1] Radiology, Department of Imaging and Pathology, UZ Leuven, Leuven, Belgium. ^[2] Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium; icometrix, R&D Department, Leuven, Belgium. ^[3] University Hospitals Leuven, Department of Neurology, Leuven, Belgium. ^[4] Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium. ^[5] University Hospitals Leuven, Department of Neurology, Leuven, Belgium; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium. ^[6] Biomedical MRI Unit/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium. Electronic address: uwe.himmelreich@kuleuven.be. ^[7]

关键词 Amyotrophic lateral sclerosis Edited MRS HERMES Magnetic resonance spectroscopy Neurodegeneration