Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts.
第一作者:
Silvia,Pignani
第一单位:
Department of Life Sciences and Biotechnology, University of Ferrara, Italy; Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
作者:
主题词
结合部位(Binding Sites);癌, 肝细胞(Carcinoma, Hepatocellular);内皮细胞(Endothelial Cells);因子Ⅶ(Factor VII);因子Ⅷ(Factor VIII);基因表达(Gene Expression);基因, 报告(Genes, Reporter);Hep G2细胞(Hep G2 Cells);肝细胞核因子4(Hepatocyte Nuclear Factor 4);人类(Humans);突变(Mutation);启动区, 遗传(Promoter Regions, Genetic);受体, 免疫(Receptors, Immunologic);转录因子(Transcription Factors);转录激活(Transcriptional Activation)
DOI
10.1016/j.bbagrm.2019.04.002
PMID
31005673
发布时间
2024-01-04
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Biochimica et biophysica acta. Gene regulatory mechanisms
2019年1862卷6期
619-624页
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