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首页> FASEB journal : official publication of the Federation of American Societies for Experimental Biology> The Tat inhibitor didehydro-cortistatin A suppresses SIV replication and reactivation.

The Tat inhibitor didehydro-cortistatin A suppresses SIV replication and reactivation.

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作者： Sonia,Mediouni ^[1] ; Cari F,Kessing ^[1] ; Joseph A,Jablonski ^[1] ; Suzie,Thenin-Houssier ^[2] ; Mark,Clementz ^[1] ; Melia D,Kovach ^[1] ; Guillaume,Mousseau ^[1] ; Ian Mitchelle S,de Vera ^[3] ; Chuan,Li ^[1] ; Douglas J,Kojetin ^[4] ; David T,Evans ^[5] ; Susana T,Valente ^[1]

作者单位： Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA. ^[1] Institute of Human Genetics (IGH), CNRS-University of Montpelier, Montpelier, France. ^[2] Department of Pharmacology and Physiology, St. Louis University School of Medicine, St. Louis, Missouri, USA. ^[3] Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida, USA. ^[4] Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[5]

关键词 block-and-lock dCA latency simian immunodeficiency virus transcription inhibition

主题词动物(Animals);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);基因产物, tat(Gene Products, tat);HEK293细胞(HEK293 Cells);人类(Humans);异喹啉类(Isoquinolines);猕猴(Macaca mulatta);启动区, 遗传(Promoter Regions, Genetic);猴获得性免疫缺陷综合征(Simian Acquired Immunodeficiency Syndrome);末端重复序列(Terminal Repeat Sequences);病毒激活(Virus Activation);病毒复制(Virus Replication)

DOI 10.1096/fj.201801165R

PMID 31021670

发布时间 2022-09-24

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FASEB journal

2019年33卷7期

8280-8293页

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