Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochondriotoxic Stress.

导出 OA

翻译打印收藏纠错

作者： Anh B,Hua ^[1] ; Rebecca,Justiniano ^[2] ; Jessica,Perer ^[3] ; Sophia L,Park ^[4] ; Hui,Li ^[5] ; Christopher M,Cabello ^[6] ; Georg T,Wondrak ^[7]

作者单位： Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. anhhua@email.arizona.edu. ^[1] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. justiniano@pharmacy.arizona.edu. ^[2] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. jperer@email.arizona.edu. ^[3] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. slpark@email.arizona.edu. ^[4] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. huili@pharmacy.arizona.edu. ^[5] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. cabello@pharmacy.arizona.edu. ^[6] Department of Pharmacology and Toxicology, College of Pharmacy & Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA. wondrak@pharmacy.arizona.edu. ^[7]

关键词 cancer experimental therapeutic melanoma oxidative stress phenazine methosulfate reactive oxygen species redox cycler

DOI 10.3390/cancers11050590

PMID 31035569

发布时间 2023-02-14

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交