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The quantitative relationship between isotopic and net contributions of lactate and glucose to the tricarboxylic acid (TCA) cycle.

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第一作者： Minfeng,Ying

第一单位： From the Cancer Institute (Key Laboratory for Cancer Intervention and Prevention, China National Ministry of Education, Zhejiang Provincial Key Laboratory of Molecular Biology in Medical Sciences), The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China.

作者： Minfeng,Ying ^[1] ; Cheng,Guo ^[1] ; Xun,Hu ^[2]

作者单位： From the Cancer Institute (Key Laboratory for Cancer Intervention and Prevention, China National Ministry of Education, Zhejiang Provincial Key Laboratory of Molecular Biology in Medical Sciences), The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China. ^[1] From the Cancer Institute (Key Laboratory for Cancer Intervention and Prevention, China National Ministry of Education, Zhejiang Provincial Key Laboratory of Molecular Biology in Medical Sciences), The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China huxun@zju.edu.cn. ^[2]

关键词 13C labeling glucose isotope exchange isotopic tracer lactic acid metabolic flux net contribution tricarboxylic acid cycle (TCA cycle) (Krebs cycle)tumor metabolism

医学主题词碳同位素(Carbon Isotopes);柠檬酸循环(Citric Acid Cycle);葡萄糖(Glucose);人类(Humans);同位素标记(Isotope Labeling);乳酸(Lactic Acid);丙酮酸(Pyruvic Acid)

DOI 10.1074/jbc.RA119.007841

PMID 31040177

发布时间 2021-02-05

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