首页> Journal of medicinal chemistry> Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.

Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.

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第一作者： Uday Kiran,Velagapudi

第一单位： Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences , St. John's University , Queens , New York 11439 , United States.

作者： Uday Kiran,Velagapudi ^[1] ; Marie-France,Langelier ^[2] ; Cristina,Delgado-Martin ^[3] ; Morgan E,Diolaiti ^[3] ; Sietske,Bakker ^[3] ; Alan,Ashworth ^[4] ; Bhargav A,Patel ^[1] ; Xuwei,Shao ^[1] ; John M,Pascal ^[2] ; Tanaji T,Talele ^[1]

作者单位： Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences , St. John's University , Queens , New York 11439 , United States. ^[1] Department of Biochemistry and Molecular Medicine , Université de Montréal , Montréal , Quebec H3T 1J4 , Canada. ^[2] UCSF Helen Diller Family Comprehensive Cancer Center , University of California , San Francisco , California 94158 , United States. ^[3] UCSF Helen Diller Family Comprehensive Cancer Center , University of California , San Francisco , California 94158 , United States.;Department of Medicine , University of California , San Francisco , California 94158 , United States. ^[4]