首页> BMJ open> Protocol for a controlled human infection with genetically modified <i>Neisseria lactamica</i> expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine.

Protocol for a controlled human infection with genetically modified <i>Neisseria lactamica</i> expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine.

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第一作者： Diane,Gbesemete

第一单位： NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.;Faculty of Medicine, University of Southampton, Southampton, UK.

作者： Diane,Gbesemete ^[1] ; Jay Robert,Laver ^[2] ; Hans,de Graaf ^[1] ; Muktar,Ibrahim ^[2] ; Andrew,Vaughan ^[2] ; Saul,Faust ^[3] ; Andrew,Gorringe ^[4] ; Robert Charles,Read ^[5]

作者单位： NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.;Faculty of Medicine, University of Southampton, Southampton, UK. ^[1] Clinical and Experimental Sciences, University of Southampton, Southampton, UK. ^[2] NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. ^[3] Research, Public Health England Porton, Salisbury, Wiltshire, UK. ^[4] Clinical and Experimental Sciences, University of Southampton, Southampton, UK.;NIHR Southampton Biomedical Research Centre, Southampton, UK. ^[5]

关键词 Neisseria lactamica colonisation genetically modified organism human challenge study