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Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction.

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第一作者： Jan,Bornschein

第一单位： MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom.;Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany.;Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, United Kingdom.

作者： Jan,Bornschein ^[1] ; Lorenz,Wernisch ^[2] ; Maria,Secrier ^[3] ; Ahmad,Miremadi ^[4] ; Juliane,Perner ^[3] ; Shona,MacRae ^[5] ; Maria,O'Donovan ^[4] ; Richard,Newton ^[2] ; Suraj,Menon ^[3] ; Lawrence,Bower ^[3] ; Matthew D,Eldridge ^[3] ; Ginny,Devonshire ^[3] ; Calvin,Cheah ^[5] ; Richard,Turkington ^[6] ; Richard H,Hardwick ^[7] ; Michael,Selgrad ^[8] ; Marino,Venerito ^[8] ; Peter,Malfertheiner ^[8] ; OCCAMS Consortium ^[5] ; Rebecca C,Fitzgerald

作者单位： MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom.;Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany.;Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, United Kingdom. ^[1] MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom. ^[2] Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom. ^[3] Department of Histopathology, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom. ^[4] MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom. ^[5] Department of Oncology, Queen's University, Northern Ireland, United Kingdom. ^[6] Department of Surgery, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom. ^[7] Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany. ^[8]

关键词 Siewert classification esophageal adenocarcinoma gastric cancer gastroesophageal junction gene expression profiling