Transient receptor potential melastatin 4 contributes to early-stage endothelial injury induced by arsenic trioxide.

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作者： Chun-Xiao,Yu ^[1] ; Yu-Yao,Zhang ^[2] ; Xia-Yang,Wu ^[3] ; Hai-Xia,Tang ^[1] ; Xue-Qi,Liang ^[1] ; Zhou-Ming,Xue ^[1] ; Ya-Dong,Xue ^[1] ; Jing,Li ^[1] ; Hui,Zhu ^[4] ; Rong,Huo ^[5] ; Tao,Ban ^[6]

作者单位： Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang, PR China. ^[1] Department of Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, PR China. ^[2] Children's Hospital of Fudan University Xiamen Branch (Xiamen Children's Hospital), Xiamen, Fujian, PR China. ^[3] Department of Physiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang, PR China. ^[4] Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang, PR China. Electronic address: huohuoz010603@163.com. ^[5] Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang, PR China. Electronic address: bantao2000@163.com. ^[6]

关键词 9-phenanthrol Arsenic trioxide Endothelial injury Human umbilical vein endothelial cells TRPM4