C57BL/6 mice immunized with synthetic peptides from Toxoplasma gondii surface and microneme immunodominant antigens are able to decrease parasite burden in the brain tissues.
第一作者:
Heber Leão Silva,Barros
第一单位:
Laboratory of Immunoparasitology Dr. Mário Endsfeldz Camargo, Institute of Biomedical Science, Federal University of Uberlândia, Uberlândia, MG, Brazil.
作者:
医学主题词
动物(Animals);抗体, 原虫(Antibodies, Protozoan);抗原, 原虫(Antigens, Protozoan);脑(Brain);细胞因子类(Cytokines);表位, B淋巴细胞(Epitopes, B-Lymphocyte);女(雌)性(Female);免疫法(Immunization);免疫显性表位(Immunodominant Epitopes);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肽类(Peptides);原虫蛋白质类(Protozoan Proteins);原虫疫苗(Protozoan Vaccines);弓形虫属(Toxoplasma);弓形虫病, 动物(Toxoplasmosis, Animal)
DOI
10.1016/j.actatropica.2019.05.003
PMID
31059707
发布时间
2019-10-29
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Acta tropica
1-6页
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