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Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries.

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第一作者： M,Asplund

第一单位： Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark. Electronic address: amasplund@snm.ku.dk.

作者： M,Asplund ^[1] ; K R,Kjartansdóttir ^[2] ; S,Mollerup ^[2] ; L,Vinner ^[2] ; H,Fridholm ^[3] ; J A R,Herrera ^[4] ; J,Friis-Nielsen ^[5] ; T A,Hansen ^[2] ; R H,Jensen ^[2] ; I B,Nielsen ^[2] ; S R,Richter ^[2] ; A,Rey-Iglesia ^[2] ; M L,Matey-Hernandez ^[5] ; D E,Alquezar-Planas ^[2] ; P V S,Olsen ^[2] ; T,Sicheritz-Pontén ^[6] ; E,Willerslev ^[2] ; O,Lund ^[5] ; S,Brunak ^[4] ; T,Mourier ^[2] ; L P,Nielsen ^[7] ; J M G,Izarzugaza ^[5] ; A J,Hansen ^[8]

作者单位： Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark. Electronic address: amasplund@snm.ku.dk. ^[1] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark. ^[2] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark; Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark. ^[3] Disease Systems Biology Programme, Panum Instituttet, Copenhagen, Denmark; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark. ^[4] Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark. ^[5] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark; Centre of Excellence for Omics-Driven Computational Biodiscovery, AIMST University, Kedah, Malaysia. ^[6] Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark. ^[7] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark. Electronic address: ajhansen@snm.ku.dk. ^[8]

关键词 Cluster Contamination High-throughput sequencing Laboratory component Metagenomic Next-generation sequencing Nucleic acid Virome Virus

医学主题词高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);宏基因组学(Metagenomics);标本制备(Specimen Handling);病毒(Viruses)

DOI 10.1016/j.cmi.2019.04.028

PMID 31059795

发布时间 2020-01-08

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准确一般字义偏差语意偏离译文作用小提交