Dronedarone (a multichannel blocker) enhances the anticonvulsant potency of lamotrigine, but not that of lacosamide, pregabalin and topiramate in the tonic-clonic seizure model in mice.

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第一作者： Katarzyna M,Sawicka

第一单位： Department of Internal Medicine in Nursing, Medical University of Lublin, Lublin, Poland; Department of Pathophysiology, Medical University of Lublin, Lublin, Poland.

作者： Katarzyna M,Sawicka ^[1] ; Magdalena,Florek-Łuszczki ^[2] ; Agnieszka,Wawryniuk ^[3] ; Jadwiga,Daniluk ^[3] ; Paula,Wróblewska-Łuczka ^[4] ; Jarosław,Chmielewski ^[5] ; Sławomir,Karwan ^[6] ; Jarogniew J,Łuszczki ^[7]

作者单位： Department of Internal Medicine in Nursing, Medical University of Lublin, Lublin, Poland; Department of Pathophysiology, Medical University of Lublin, Lublin, Poland. ^[1] Department of Medical Anthropology, Institute of Rural Health, Lublin, Poland. ^[2] Department of Internal Medicine in Nursing, Medical University of Lublin, Lublin, Poland. ^[3] Department of Pathophysiology, Medical University of Lublin, Lublin, Poland. ^[4] Institute of Environmental Protection - National Research Institute in Warsaw, Poland. ^[5] Regional Specialized Children's Hospital, Olsztyn, Poland. ^[6] Department of Pathophysiology, Medical University of Lublin, Lublin, Poland. Electronic address: jluszczki@yahoo.com. ^[7]

关键词 Antiepileptic drugs Dronedarone Maximal electroshock-induced seizures