Role of endothelin-1 clearance in the haemodynamic responses to endothelin-1 in the pulmonary and hindquarter vasculature of anaesthetised rats.
第一作者:
James A,Angus
第一单位:
Cardiovascular Therapeutics Unit, Department of Pharmacology and Therapeutics, University of Melbourne, Victoria 3010, Australia. Electronic address: jamesaa@unimelb.edu.au.
作者:
关键词
AmbrisentanAmbrisentan (PubChem CID: 6918493)BQ788 (PubChem CID: 3081333)BosentanBosentan sodium (PubChem CID: 44387533)ET(1)-Receptor antagonistsEndothelin clearanceEndothelin-1Endothelin-1 (PubChem CID: 16132423)Hindquarter vascular constrictionMacitentanMacitentan (PubChem CID: 16004692)Pulmonary vascular constrictionSarafotoxin S6CSarafotoxin S6C (PubChem CID: 16132429)
主题词
麻醉(Anesthesia);动物(Animals);药物相互作用(Drug Interactions);内皮缩血管肽1(Endothelin-1);女(雌)性(Female);血流动力学(Hemodynamics);肺(Lung);男(雄)性(Male);NG-硝基精氨酸甲酯(NG-Nitroarginine Methyl Ester);新生血管化, 生理性(Neovascularization, Physiologic);嘧啶类(Pyrimidines);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);磺胺类(Sulfonamides);蝰蛇毒液类(Viper Venoms)
DOI
10.1016/j.ejphar.2019.05.009
PMID
31063771
发布时间
2019-12-20
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