首页> The Journal of clinical investigation> Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.

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第一作者： Elena,Vezzoli

第一单位： Department of Biosciences, University of Milan, Milan, Italy.;Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan, Italy.

作者： Elena,Vezzoli ^[1] ; Ilaria,Caron ^[1] ; Francesca,Talpo ^[2] ; Dario,Besusso ^[1] ; Paola,Conforti ^[1] ; Elisa,Battaglia ^[1] ; Elisa,Sogne ^[3] ; Andrea,Falqui ^[3] ; Lara,Petricca ^[4] ; Margherita,Verani ^[4] ; Paola,Martufi ^[4] ; Andrea,Caricasole ^[4] ; Alberto,Bresciani ^[4] ; Ottavia,Cecchetti ^[4] ; Pia,Rivetti di Val Cervo ^[1] ; Giulio,Sancini ^[5] ; Olaf,Riess ^[6] ; Hoa,Nguyen ^[6] ; Lisa,Seipold ^[7] ; Paul,Saftig ^[7] ; Gerardo,Biella ^[2] ; Elena,Cattaneo ^[1] ; Chiara,Zuccato ^[1]

作者单位： Department of Biosciences, University of Milan, Milan, Italy.;Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan, Italy. ^[1] Department of Biology and Biotechnologies, University of Pavia, Pavia, Italy. ^[2] King Abdullah University of Science and Technology (KAUST), Biological and Environmental Science & Engineering (BESE) Division, NABLA Lab, Thuwal, Saudi Arabia. ^[3] IRBM Science Park SpA, Pomezia, Italy. ^[4] School of Medicine and Surgery, Nanomedicine Center, Neuroscience Center, University of Milano-Bicocca, Monza, Italy. ^[5] Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany. ^[6] Institute of Biochemistry, Christian Albrechts University of Kiel, Kiel, Germany. ^[7]

关键词 Neurodegeneration Neuroscience Synapses