Evaluation of potential biotin interference in immunogenicity testing.

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第一作者： Alexander,Pöhler

第一单位： Roche Pharma Research & Early Development (pRED), Pharmaceutical Sciences, Bioanalytical R&D, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany.

作者： Alexander,Pöhler ^[1] ; Janine,Faigle ^[1] ; Roland F,Staack ^[1]

作者单位： Roche Pharma Research & Early Development (pRED), Pharmaceutical Sciences, Bioanalytical R&D, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany. ^[1]

关键词 ELISA antidrug antibody biotin immunogenicity interference

主题词动物(Animals);抗体(Antibodies);生物素(Biotin);人类(Humans);免疫学技术(Immunologic Techniques);药用制剂(Pharmaceutical Preparations)

DOI 10.4155/bio-2019-0080

PMID 31070046

发布时间 2020-03-18

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