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NMR-Based Metabolic Profiles of Intact Zebrafish Embryos Exposed to Aflatoxin B1 Recapitulates Hepatotoxicity and Supports Possible Neurotoxicity.

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第一作者： Zain,Zuberi

第一单位： The School of Pharmacy and Pharmaceutical Sciences, Trinity College, D02 PN40 Dublin, Ireland. zuberiz@tcd.ie.;Leiden Institute of Chemistry, Leiden University, 2333 Leiden, The Netherlands. zuberiz@tcd.ie.

作者： Zain,Zuberi ^[1] ; Muhamed N H,Eeza ^[2] ; Joerg,Matysik ^[3] ; John P,Berry ^[4] ; A,Alia ^[5]

作者单位： The School of Pharmacy and Pharmaceutical Sciences, Trinity College, D02 PN40 Dublin, Ireland. zuberiz@tcd.ie.;Leiden Institute of Chemistry, Leiden University, 2333 Leiden, The Netherlands. zuberiz@tcd.ie. ^[1] Institute for Medical Physics and Biophysics, University of Leipzig, 04107 Leipzig, Germany. MuhamedNour.HashemEeza@medizin.uni-leipzig.de.;Institute for Analytical Chemistry, University of Leipzig, 04107 Leipzig, Germany. MuhamedNour.HashemEeza@medizin.uni-leipzig.de. ^[2] Institute for Analytical Chemistry, University of Leipzig, 04107 Leipzig, Germany. joerg.matysik@uni-leipzig.de. ^[3] Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33181, USA. berryj@fiu.edu. ^[4] Leiden Institute of Chemistry, Leiden University, 2333 Leiden, The Netherlands. Alia.AliaMatysik@medizin.uni-leipzig.de.;Institute for Medical Physics and Biophysics, University of Leipzig, 04107 Leipzig, Germany. Alia.AliaMatysik@medizin.uni-leipzig.de. ^[5]

关键词 aflatoxin B1 biomarkers high-resolution magic angle spin (HRMAS)metabolomics nuclear magnetic resonance (NMR)zebrafish