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A comprehensive review of the clinical utility of and a combined analysis of the clozapine/norclozapine ratio in therapeutic drug monitoring for adult patients.

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第一作者： Georgios,Schoretsanitis

第一单位： a Zucker Hillside Hospital, Psychiatry Research, Northwell Health , Glen Oaks , NY , USA.;b Hofstra Northwell School of Medicine , Hempstead , NY , USA.;c Feinstein Institute for Medical Research , Manhasset , NY , USA.

作者： Georgios,Schoretsanitis ^[1] ; John M,Kane ^[1] ; Can-Jun,Ruan ^[2] ; Edoardo,Spina ^[3] ; Christoph,Hiemke ^[4] ; Jose,de Leon ^[5]

作者单位： a Zucker Hillside Hospital, Psychiatry Research, Northwell Health , Glen Oaks , NY , USA.;b Hofstra Northwell School of Medicine , Hempstead , NY , USA.;c Feinstein Institute for Medical Research , Manhasset , NY , USA. ^[1] d Laboratory of Clinical Psychopharmacology & The National Clinical Research Centre for Mental Disorders & Beijing Key Lab of Mental Disorders, Beijing Anding Hospital , Capital Medical University , Beijing , China. ^[2] e Department of Clinical and Experimental Medicine , University of Messina , Messina , Italy. ^[3] f Department of Psychiatry and Psychotherapy , University Medical Center of Mainz , Mainz , Germany. ^[4] g University of Kentucky Mental Health Research Center at Eastern State Hospital , Lexington , KY , USA.;h Psychiatry and Neurosciences Research Group (CTS-549), Institute of Neurosciences, University of Granada , Granada , Spain.;i Biomedical Research Centre in Mental Health Net (CIBERSAM), Santiago Apostol Hospital, University of the Basque Country , Vitoria , Spain. ^[5]

关键词 Antipsychotic agents/pharmacology clozapine drug monitoring norclozapine schizophrenia

医学主题词成年人(Adult);动物(Animals);抗精神病药(Antipsychotic Agents);氯氮平(Clozapine);药物监测(Drug Monitoring);人类(Humans);随机对照试验(主题)(Randomized Controlled Trials as Topic)

DOI 10.1080/17512433.2019.1617695

PMID 31075044

发布时间 2019-07-04

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