CD8β Depletion Does Not Prevent Control of Viral Replication or Protection from Challenge in Macaques Chronically Infected with a Live Attenuated Simian Immunodeficiency Virus.

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作者： Matthew S,Sutton ^[1] ; Amy,Ellis-Connell ^[1] ; Alexis J,Balgeman ^[1] ; Gabrielle,Barry ^[2] ; Andrea M,Weiler ^[2] ; Scott J,Hetzel ^[3] ; Yan,Zhou ^[4] ; Annie W,Lau-Kilby ^[4] ; Rosemarie D,Mason ^[4] ; Kristin K,Biris ^[4] ; John R,Mascola ^[4] ; Nancy J,Sullivan ^[4] ; Mario,Roederer ^[4] ; Thomas C,Friedrich ^[5] ; Shelby L,O'Connor ^[6]

作者单位： Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[1] Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[2] Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[3] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. ^[4] Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.;Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[5] Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA slfeinberg@wisc.edu.;Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA. ^[6]

关键词 CD8αβ+ T cells cynomolgus macaques depletion live-attenuated SIV