Assessment of a defined approach based on a stacking prediction model to identify skin sensitization hazard.

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作者： Fleur,Tourneix ^[1] ; Nathalie,Alépée ^[2] ; Ann,Detroyer ^[2] ; Joan,Eilstein ^[2] ; Silvia,Martinozzi Teissier ^[2] ; Laurent,Nardelli ^[2] ; Hicham,Noçairi ^[2] ; Thierry,Pauloin ^[2] ; Cécile,Piroird ^[2] ; Aurélia,Del Bufalo ^[2]

作者单位： L'Oréal Research & Innovation, Aulnay-sous-Bois, France. Electronic address: fleur.tourneix@rd.loreal.com. ^[1] L'Oréal Research & Innovation, Aulnay-sous-Bois, France. ^[2]

关键词 Defined approach Hazard identification In silico In vitro Risk assessment Skin sensitization

主题词动物替代试验(Animal Testing Alternatives);计算机模拟(Computer Simulation);数据库, 事实型(Databases, Factual);皮炎, 变应性接触性(Dermatitis, Allergic Contact);半抗原(Haptens);人类(Humans);模型, 生物学(Models, Biological)

DOI 10.1016/j.tiv.2019.05.008

PMID 31100378

发布时间 2020-02-10

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准确一般字义偏差语意偏离译文作用小提交