Exposure time versus cytotoxicity for anticancer agents.

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第一作者： David M,Evans

第一单位： Molecular Pharmacology Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.

作者： David M,Evans ^[1] ; Jianwen,Fang ^[2] ; Thomas,Silvers ^[1] ; Rene,Delosh ^[1] ; Julie,Laudeman ^[1] ; Chad,Ogle ^[1] ; Russell,Reinhart ^[1] ; Michael,Selby ^[1] ; Lori,Bowles ^[1] ; John,Connelly ^[1] ; Erik,Harris ^[1] ; Julia,Krushkal ^[2] ; Larry,Rubinstein ^[2] ; James H,Doroshow ^[3] ; Beverly A,Teicher ^[4]

作者单位： Molecular Pharmacology Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA. ^[1] Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, 20852, USA. ^[2] Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, 20852, USA. ^[3] Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, 20852, USA. Beverly.Teicher@nih.gov. ^[4] Molecular Pharmacology Branch, National Cancer Institute, RM 4-W602, MSC 9735, 9609 Medical Center Drive, Bethesda, MD, 20892, USA. Beverly.Teicher@nih.gov. ^[5]

关键词 Concentration times time CxT Epigenetic agents NCI60

主题词抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans)

DOI 10.1007/s00280-019-03863-w

PMID 31102023

发布时间 2024-06-15

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准确一般字义偏差语意偏离译文作用小提交