SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

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作者： Lea H,Gregersen ^[1] ; Richard,Mitter ^[2] ; Alejandro P,Ugalde ^[3] ; Takayuki,Nojima ^[4] ; Nicholas J,Proudfoot ^[4] ; Reuven,Agami ^[3] ; Aengus,Stewart ^[2] ; Jesper Q,Svejstrup ^[5]

作者单位： Mechanisms of Transcription Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. ^[1] Bioinformatics and Biostatistics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. ^[2] The Netherlands Cancer Institute (NKI-AVL), Plesmanlaan 121, 1066 CX Amsterdam, Netherlands. ^[3] Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE Oxford, UK. ^[4] Mechanisms of Transcription Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: jesper.svejstrup@crick.ac.uk. ^[5]

关键词 C-terminal repeat domain (CTD)CTD phosphorylation RNA polymerase II SCAF4 SCAF8 anti-termination co-transcriptional mRNA processing polyadenylation transcript elongation transcriptional termination

主题词 HEK293细胞(HEK293 Cells);人类(Humans);聚腺苷酸类(Poly A);RNA聚合酶Ⅱ(RNA Polymerase II);RNA, 信使(RNA, Messenger);RNA结合蛋白质类(RNA-Binding Proteins)

DOI 10.1016/j.cell.2019.04.038

PMID 31104839

发布时间 2024-04-18

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