Quercetin-3-oleoyl derivatives as new GPR40 agonists: Molecular docking studies and functional evaluation.

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作者： Gabriele,Carullo ^[1] ; Mariarita,Perri ^[1] ; Fabrizio,Manetti ^[2] ; Francesca,Aiello ^[3] ; Maria Cristina,Caroleo ^[1] ; Erika,Cione ^[1]

作者单位： Department of Pharmacy, Health and Nutritional Sciences, "Dipartimento di Eccellenza 2018-2022", University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy. ^[1] Department of Biotechnology, Chemistry and Pharmacy, "Dipartimento di Eccellenza 2018-2022", University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy. ^[2] Department of Pharmacy, Health and Nutritional Sciences, "Dipartimento di Eccellenza 2018-2022", University of Calabria, Edificio Polifunzionale, 87036 Rende, Italy. Electronic address: francesca.aiello@unical.it. ^[3]

关键词 GPR40 allosteric site Insulin secretion Oleic acid Quercetin Type 2 diabetes

主题词人类(Humans);槲皮素(Quercetin)

DOI 10.1016/j.bmcl.2019.05.018

PMID 31104992

发布时间 2020-09-09

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