Direct comparison of chitinolytic properties and determination of combinatory effects of mouse chitotriosidase and acidic mammalian chitinase.

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第一作者： Masahiro,Kimura

第一单位： Department of Chemistry and Life Science, Kogakuin University, Hachioji, Tokyo, Japan; Research Fellow of Japan Society for the Promotion of Science (DC2), Koujimachi, Chiyoda-ku, Tokyo 102-0083, Japan.

作者： Masahiro,Kimura ^[1] ; Takatoshi,Umeyama ^[2] ; Satoshi,Wakita ^[2] ; Kazuaki,Okawa ^[2] ; Masayoshi,Sakaguchi ^[2] ; Vaclav,Matoska ^[3] ; Peter O,Bauer ^[4] ; Fumitaka,Oyama ^[5]

作者单位： Department of Chemistry and Life Science, Kogakuin University, Hachioji, Tokyo, Japan; Research Fellow of Japan Society for the Promotion of Science (DC2), Koujimachi, Chiyoda-ku, Tokyo 102-0083, Japan. ^[1] Department of Chemistry and Life Science, Kogakuin University, Hachioji, Tokyo, Japan. ^[2] Laboratory of Molecular Diagnostics, Department of Clinical Biochemistry, Hematology and Immunology, Homolka Hospital, Roentgenova 37/2, Prague 150 00, Czech Republic. ^[3] Laboratory of Molecular Diagnostics, Department of Clinical Biochemistry, Hematology and Immunology, Homolka Hospital, Roentgenova 37/2, Prague 150 00, Czech Republic; Bioinova Ltd., Videnska 1083, Prague 142 20, Czech Republic. ^[4] Department of Chemistry and Life Science, Kogakuin University, Hachioji, Tokyo, Japan. Electronic address: f-oyama@cc.kogakuin.ac.jp. ^[5]

关键词 Acidic mammalian chitinase Chitin substrates Chitotriosidase Direct comparison Mutual effects Serratia marcescens chitinase B