Effect of Targeting Mean Arterial Pressure During Cardiopulmonary Bypass by Monitoring Cerebral Autoregulation on Postsurgical Delirium Among Older Patients: A Nested Randomized Clinical Trial.

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作者： Charles H,Brown ^[1] ; Karin J,Neufeld ^[2] ; Jing,Tian ^[3] ; Julia,Probert ^[4] ; Andrew,LaFlam ^[5] ; Laura,Max ^[6] ; Daijiro,Hori ^[7] ; Yohei,Nomura ^[7] ; Kaushik,Mandal ^[8] ; Ken,Brady ^[9] ; Charles W,Hogue ^[10] ; Cerebral Autoregulation Study Group ^[11] ; Ashish,Shah ^[12] ; Kenton,Zehr ^[13] ; Duke,Cameron ^[8] ; John,Conte ^[2] ; O Joseph,Bienvenu ^[14] ; Rebecca,Gottesman ^[15] ; Atsushi,Yamaguchi ^[16] ; Michael,Kraut

作者单位： Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[1] Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[2] Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. ^[3] School of Medicine, New York University, New York. ^[4] Medical Student, School of Medicine, Tufts University, Medford Massachusetts. ^[5] Department of Radiology, Massachusetts General Hospital, Boston. ^[6] Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan. ^[7] Division of Cardiac Surgery, Department of Surgery, Penn State University Hershey Medical Center, Hershey, Pennsylvania. ^[8] Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. ^[9] Bluhm Cardiovascular Institute, Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. ^[10] Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee. ^[11] Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[12] Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston. ^[13] Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[14] Saitama Medical Center, Jichi Medical University, Saitama, Japan. ^[15] Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[16]

主题词医学科学研究中心(Academic Medical Centers);年龄因素(Age Factors);老年人(Aged);心肺转流术(Cardiopulmonary Bypass);脑血管循环(Cerebrovascular Circulation);谵妄(Delirium);女(雌)性(Female);老年人身心健康评价(Geriatric Assessment);内环境稳定(Homeostasis);人类(Humans);发病率(Incidence);男(雄)性(Male);中年人(Middle Aged);监测, 手术中(Monitoring, Intraoperative);手术后并发症(Postoperative Complications);前瞻性研究(Prospective Studies);参考值(Reference Values);疾病严重程度指数(Severity of Illness Index);性别因素(Sex Factors)

DOI 10.1001/jamasurg.2019.1163

PMID 31116358

发布时间 2021-06-12

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JAMA surgery

2019年154卷9期

819-826页

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Effect of Targeting Mean Arterial Pressure During Cardiopulmonary Bypass by Monitoring Cerebral Autoregulation on Postsurgical Delirium Among Older Patients: A Nested Randomized Clinical Trial.

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Effect of Targeting Mean Arterial Pressure During Cardiopulmonary Bypass by Monitoring Cerebral Autoregulation on Postsurgical Delirium Among Older Patients: A Nested Randomized Clinical Trial.

JAMA surgery

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JAMA surgery

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