作者：
Raiees,Andrabi [1]
;
Jesper,Pallesen [2]
;
Joel D,Allen [3]
;
Ge,Song [1]
;
Jinsong,Zhang [4]
;
Natalia,de Val [5]
;
Gavin,Gegg [1]
;
Katelyn,Porter [1]
;
Ching-Yao,Su [1]
;
Matthias,Pauthner [1]
;
Amanda,Newman [4]
;
Hilary,Bouton-Verville [4]
;
Fernando,Garces [5]
;
Ian A,Wilson [6]
;
Max,Crispin [3]
;
Beatrice H,Hahn [7]
;
Barton F,Haynes [8]
;
Laurent,Verkoczy [9]
;
Andrew B,Ward [10]
;
Dennis R,Burton [11]
作者单位：
Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
[1]
International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
[2]
International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; School of Biological Sciences, University of Southampton, Southampton, UK.
[3]
Duke Human Vaccine Institute and Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA.
[4]
International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
[5]
International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
[6]
Departments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
[7]
Duke Human Vaccine Institute and Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA.
[8]
Duke Human Vaccine Institute and Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA; San Diego Biomedical Research Institute, San Diego, CA 92121, USA.
[9]
International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: andrew@scripps.edu.
[10]
Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02114, USA. Electronic address: burton@scripps.edu.
[11]
主题词
艾滋病疫苗(AIDS Vaccines);动物(Animals);抗体, 中和(Antibodies, Neutralizing);抗原抗体反应(Antigen-Antibody Reactions);冷冻电子显微镜检查(Cryoelectron Microscopy);基因产物, env(Gene Products, env);糖基化(Glycosylation);HIV抗体(HIV Antibodies);人类(Humans);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 动物(Models, Animal);诱变, 定点(Mutagenesis, Site-Directed);黑猩猩属(Pan troglodytes);前体细胞, B淋巴样(Precursor Cells, B-Lymphoid);蛋白质工程(Protein Engineering);蛋白质结构, 四级(Protein Structure, Quaternary);重组蛋白质类(Recombinant Proteins)
DOI
10.1016/j.celrep.2019.04.082
PMID
31116986
发布时间
2022-03-09
换一批
换一批
