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首页> FASEB journal : official publication of the Federation of American Societies for Experimental Biology> Assessment of mitophagy in mt-Keima <i>Drosophila</i> revealed an essential role of the PINK1-Parkin pathway in mitophagy induction <i>in vivo</i>.

Assessment of mitophagy in mt-Keima <i>Drosophila</i> revealed an essential role of the PINK1-Parkin pathway in mitophagy induction <i>in vivo</i>.

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作者： Young Yeon,Kim ^[1] ; Jee-Hyun,Um ^[2] ; Jeong-Hyun,Yoon ^[1] ; Hyunjin,Kim ^[2] ; Da-Ye,Lee ^[1] ; Yoon Jung,Lee ^[2] ; Hye Jin,Jee ^[1] ; Young Mi,Kim ^[3] ; Jae Sung,Jang ^[1] ; Yoon-Gu,Jang ^[2] ; Jongkyeong,Chung ^[1] ; Hwan Tae,Park ^[2] ; Toren,Finkel ^[1] ; Hyongjong,Koh ^[2] ; Jeanho,Yun ^[1]

作者单位： Peripheral Neuropathy Research Center, College of Medicine, Dong-A University, Busan, Korea. ^[1] Department of Biochemistry, College of Medicine, Dong-A University, Busan, Korea. ^[2] Department of Pharmacology, College of Medicine, Dong-A University, Busan, Korea. ^[3] National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea. ^[4] Department of Molecular Neuroscience, College of Medicine, Dong-A University, Busan, Korea. ^[5] Department of Medicine, Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[6]

关键词 Drosophila model confocal microscopy in vivo mitophagy quantitation of mitophagy

主题词动物(Animals);动物, 基因修饰(Animals, Genetically Modified);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);基因表达调控(Gene Expression Regulation);基因型(Genotype);信号传导(Signal Transduction);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1096/fj.201900073R

PMID 31120803

发布时间 2024-05-11

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FASEB journal

2019年33卷9期

9742-9751页

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