首页> International immunopharmacology> Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy.

Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy.

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第一作者： Feng,Zhan

第一单位： Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Hepatobiliary and Laparoscopic Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing 214200, China.

作者： Feng,Zhan ^[1] ; Guoping,Zhao ^[2] ; Xu,Li ^[3] ; Shikun,Yang ^[3] ; Wenjie,Yang ^[3] ; Shun,Zhou ^[4] ; Feng,Zhang ^[5]

作者单位： Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Hepatobiliary and Laparoscopic Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing 214200, China. ^[1] Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of General Surgery, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 210029, China. ^[2] Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. ^[3] Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: hand2399@163.com. ^[4] Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: zhangfeng1958@hotmail.com. ^[5]

关键词 Acute liver injury Autophagy Endoplasmic reticulum stress Inflammation Oxidative stress STF-083010