Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells.

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作者： Mohamed E M,Saeed ^[1] ; Joelle C,Boulos ^[1] ; Gihan,Elhaboub ^[2] ; Daniela,Rigano ^[3] ; Antoine,Saab ^[4] ; Monica R,Loizzo ^[5] ; Loiy E A,Hassan ^[6] ; Yoshikazu,Sugimoto ^[7] ; Sonia,Piacente ^[8] ; Rosa,Tundis ^[5] ; Sakina,Yagi ^[2] ; Hassan,Khalid ^[9] ; Thomas,Efferth ^[10]

作者单位： Department of Pharmaceutical Biology, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany. ^[1] Department of Botany, Faculty of Science, University of Khartoum, Khartoum, Sudan. ^[2] Department of Pharmacy, University Federico II of Naples, via Domenico Montesano 49, 80131 Naples, Italy. ^[3] Department of Biology, Faculty of Science II and Faculty of Agriculture and Veterinary Medicine, Lebanese University, Beirut, Lebanon. ^[4] Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (Cosenza), Italy. ^[5] Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800, Malaysia. ^[6] Division of Chemotherapy, Faculty of Pharmacy, Keio University, Tokyo, Japan. ^[7] Department of Pharmacy, University of Salerno, Via Giovanni Paolo II n. 132, 84084 Fisciano, SA, Italy. ^[8] Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan. ^[9] Department of Pharmaceutical Biology, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany. Electronic address: efferth@uni-mainz.de. ^[10]

关键词 Cancer Citrullus colocynthis Drug resistance Microarray Traditional herbal medicine