Cellular circadian period length inversely correlates with HbA<sub>1c</sub> levels in individuals with type 2 diabetes.

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作者： Flore,Sinturel ^[1] ; Anne-Marie,Makhlouf ^[2] ; Patrick,Meyer ^[3] ; Christel,Tran ^[4] ; Zoltan,Pataky ^[1] ; Alain,Golay ^[2] ; Guillaume,Rey ^[3] ; Cédric,Howald ^[4] ; Emmanouil T,Dermitzakis ^[1] ; Claude,Pichard ^[1] ; Jacques,Philippe ^[5] ; Steven A,Brown ^[6] ; Charna,Dibner ^[6]

作者单位： Department of Medicine, Division of Endocrinology, Diabetes, Hypertension and Nutrition, Faculty of Medicine, University of Geneva, Rue Michel-Servet, 1, CH-1211, 14, Geneva, Switzerland. ^[1] Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. ^[2] Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland. ^[3] Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland. ^[4] Center for Molecular Diseases, Division of Genetic Medicine, Lausanne University Hospital, Lausanne, Switzerland. ^[5] Division for Therapeutic Patient Education for Chronic Diseases, University Hospital of Geneva, Geneva, Switzerland. ^[6] Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland. ^[7] Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. ^[8] Department of Medicine, Division of Endocrinology, Diabetes, Hypertension and Nutrition, Faculty of Medicine, University of Geneva, Rue Michel-Servet, 1, CH-1211, 14, Geneva, Switzerland. Charna.Dibner@hcuge.ch. ^[9] Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Charna.Dibner@hcuge.ch. ^[10] Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Charna.Dibner@hcuge.ch. ^[11] Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland. Charna.Dibner@hcuge.ch. ^[12]

关键词 Circadian bioluminescence recording Circadian clock HbA1c Humans ICAM1 Type 2 diabetes