换一批A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG).
第一作者：
Huachao,Huang
第一单位：
Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA.
作者：
医学主题词
氨基吡啶类(Aminopyridines);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);细胞, 培养的(Cells, Cultured);双加氧酶类(Dioxygenases);基因表达调控, 病毒(Gene Expression Regulation, Viral);HEK293细胞(HEK293 Cells);HIV感染(HIV Infections);HIV-1(HIV-1);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白脱甲基酶类(Histone Demethylases);组蛋白类(Histones);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);腙类(Hydrazones);甲基化(Methylation);核蛋白质类(Nuclear Proteins);RNA干扰(RNA Interference);病毒潜伏期(Virus Latency)
DOI
10.1093/nar/gkz493
PMID
31165872
发布时间
2020-03-09
- 浏览1
Nucleic acids research
7333-7347页
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