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Supercharging adoptive T cell therapy to overcome solid tumor-induced immunosuppression.

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第一作者： Sherly,Mardiana

第一单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.;Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia.

作者： Sherly,Mardiana ^[1] ; Benjamin J,Solomon ^[2] ; Phillip K,Darcy ^[3] ; Paul A,Beavis ^[4]

作者单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.;Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia. ^[1] Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia.;Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.;Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia. ^[2] Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia. paul.beavis@petermac.org phil.darcy@petermac.org.;Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia.;Department of Pathology, University of Melbourne, Parkville, Victoria 3010, Australia.;Department of Immunology, Monash University, Clayton, Victoria 3168, Australia. ^[3] Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia. paul.beavis@petermac.org phil.darcy@petermac.org.;Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia. ^[4]

医学主题词动物(Animals);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);肿瘤(Neoplasms);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);T淋巴细胞(T-Lymphocytes)

DOI 10.1126/scitranslmed.aaw2293

PMID 31167925

发布时间 2021-12-04

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