首页> International journal of biological sciences> Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer.

Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer.

导出 OA

翻译打印收藏纠错

第一作者： Hongtao,Wang

第一单位： Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.;State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300200, China.

作者： Hongtao,Wang ^[1] ; Fang,Huang ^[2] ; Zhe,Zhang ^[2] ; Peng,Wang ^[2] ; Yuan,Luo ^[3] ; Hailiang,Li ^[4] ; Na,Li ^[2] ; Jian,Wang ^[2] ; Jianguang,Zhou ^[2] ; Yongan,Wang ^[3] ; Shanhu,Li ^[2]

作者单位： Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.;State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300200, China. ^[1] Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China. ^[2] State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China. ^[3] Zhuhai People's Hospital, Zhuhai Hospital Affiliated Jinan University, Zhuhai 519000, China. ^[4]

关键词 4EBP1 AKT SGK3 breast cancer mTOR rapamycin resistance