Rapid single B cell antibody discovery using nanopens and structured light.

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作者： Aaron,Winters ^[1] ; Karyn,McFadden ^[1] ; John,Bergen ^[2] ; Julius,Landas ^[2] ; Kelly A,Berry ^[3] ; Anthony,Gonzalez ^[2] ; Hossein,Salimi-Moosavi ^[1] ; Christopher M,Murawsky ^[1] ; Philip,Tagari ^[3] ; Chadwick T,King ^[2]

作者单位： a Department of Therapeutic Discovery, Amgen Research , Thousand Oaks , CA , USA. ^[1] b Department of Therapeutic Discovery, Amgen Research , Burnaby , Canada. ^[2] c Department of Pharmacokinetics & Drug Metabolism, University of British Columbia , Vancouver , Canada. ^[3]

关键词 ASC ELISA Monoclonal antibody NanOBlast OEP OptoElectro Positioning antibody discovery antibody generation nanofluidics structured light

主题词动物(Animals);抗体, 单克隆, 鼠源性(Antibodies, Monoclonal, Murine-Derived);B-淋巴细胞(B-Lymphocytes);CHO细胞(CHO Cells);仓鼠属(Cricetulus);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);人类(Humans);免疫球蛋白G(Immunoglobulin G);小鼠(Mice)

DOI 10.1080/19420862.2019.1624126

PMID 31185801

发布时间 2020-02-25

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Rapid single B cell antibody discovery using nanopens and structured light.

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Rapid single B cell antibody discovery using nanopens and structured light.

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