Infiltrating CCR2<sup>+</sup> monocytes and their progenies, fibrocytes, contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1.

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作者： Naoki,Kuroda ^[1] ; Masahiro,Masuya ^[2] ; Isao,Tawara ^[1] ; Junya,Tsuboi ^[1] ; Misao,Yoneda ^[3] ; Kenichiro,Nishikawa ^[4] ; Yuki,Kageyama ^[1] ; Kensuke,Hachiya ^[1] ; Kohshi,Ohishi ^[5] ; Hiroshi,Miwa ^[1] ; Reiko,Yamada ^[6] ; Yasuhiko,Hamada ^[6] ; Kyosuke,Tanaka ^[6] ; Takuma,Kato ^[7] ; Yoshiyuki,Takei ^[6] ; Naoyuki,Katayama ^[1]

作者单位： Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Mie, 514-8507, Japan. ^[1] Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Mie, 514-8507, Japan. mmasuya@clin.medic.mie-u.ac.jp. ^[2] Department of Clinical Nutrition Medical Technology Course, Suzuka University of Medical Science, Suzuka, Mie, 510-0293, Japan. ^[3] Department of Internal Medicine, Matsusaka City Hospital, Matsusaka, Mie, 515-8544, Japan. ^[4] Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, Tsu, Mie, 514-8507, Japan. ^[5] Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Mie, 514-8507, Japan. ^[6] Department of Cellular and Molecular Immunology, Mie University Graduate School of Medicine, Tsu, Mie, 514-8507, Japan. ^[7]