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Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters.

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第一作者： Felix,Sigmund

第一单位： Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.;Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.;Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.

作者： Felix,Sigmund ^[1] ; Susanne,Pettinger ^[1] ; Massimo,Kube ^[2] ; Fabian,Schneider ^[2] ; Martina,Schifferer ^[3] ; Steffen,Schneider ^[4] ; Maria V,Efremova ^[5] ; Jesús,Pujol-Martí ^[6] ; Michaela,Aichler ^[7] ; Axel,Walch ^[7] ; Thomas,Misgeld ^[3] ; Hendrik,Dietz ^[2] ; Gil G,Westmeyer ^[1]

作者单位： Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.;Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.;Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany. ^[1] Laboratory for Biomolecular Design, Department of Physics , Technical University of Munich , 85748 Garching , Germany. ^[2] Institute of Neuronal Cell Biology, TUM School of Medicine , Technical University of Munich , 80802 Munich , Germany.;German Center for Neurodegenerative Diseases (DZNE) , 81377 Munich , Germany. ^[3] Computational Neuroengineering, Department of Electrical and Computer Engineering , Technical University of Munich , 80333 Munich , Germany.;Tübingen AI Center , University of Tübingen , 72076 Tübingen , Germany. ^[4] Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.;Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.;Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.;Laboratory of Chemical Design of Bionanomaterials for Medical Applications, Department of Chemistry , Lomonosov Moscow State University , 119991 Moscow , Russian Federation. ^[5] Department "Circuits - Computation - Models" , Max Planck Institute of Neurobiology , 82152 Martinsried , Germany. ^[6] Research Unit Analytical Pathology , Helmholtz Zentrum München , 85764 Neuherberg , Germany. ^[7]

关键词 compartmentalization cryo-electron microscopy electron microscopy encapsulin gene reporter iron biomineralization multiplexing